Premix membrane emulsification for the preparation of curcumin-loaded nanoemulsions

Uniform-sized PLA nanoparticles: preparation by premix membrane emulsification.

Nanoparticle size is crucial to drug release behavior and biodistribution in vivo, but few studies have been performed on biodegradable nanoparticles with narrow size distribution. In this note, uniform-sized nanoparticles were prepared by a facile method combining emulsion-solvent removal and premix membrane emulsification for the first time. After preparation of coarse emulsions, additional p...

On the preparation of lecithin-stabilized oil-in-water emulsions by multi-stage premix membrane emulsification

Preparation and In Vivo Evaluation of Indomethacin Loaded True Nanoemulsions

Indomethacin, a potent nonsteroidal anti-inflammatory drug, has been used in the treatment of various kinds of pains, inflammation and arthritis. However, oral administration of indomethacin produces serious gastrointestinal adverse effects. Therefore the aim of the present investigation was to evaluate the anti-inflammatory effects, skin irritation, activation energy and histopathology of indo...

Extreme emulsification: formation and structure of nanoemulsions

Nanoemulsions are metastable dispersions of nanodroplets of one liquid that have been ruptured by shear in another immiscible liquid. The ruptured droplets are stabilized against subsequent coalescence by a surfactant. Because the nanodroplets do not form spontaneously, as they can in lyotropic “microemulsion” phases, the structure of nanoemulsions is primarily dependent on the history of the a...

Preparation of uniform particle-stabilized emulsions using SPG membrane emulsification.

Various aspects of particle-stabilized emulsions (or so-called Pickering emulsions) have been extensively investigated during the last two decades, but the preparation of uniform Pickering emulsion droplets via a simple and scalable method has been sparingly realized. We report the preparation of uniform Pickering emulsions by Shirasu porous glass (SPG) membrane emulsification. The size of the ...